Torque-Induced Rotational Dynamics in Polymers: Torsional Blobs and Thinning
By using the blob theory and computer simulations, we investigate the properties of a linear polymer performing a stationary rotational motion around a long impenetrable rod. In particular, in the simulations the rotation is induced by a torque applied to the end of the polymer that is tethered to the rod. Three different regimes are found, in close analogy with the case of polymers pulled by a constant force at one end. For low torques the polymer rotates maintaining its equilibrium conformation. At intermediate torques the polymer assumes a trumpet shape, being composed by blobs of increasing size. At even larger torques the polymer is partially wrapped around the rod. We derive several scaling relations between various quantities as angular velocity, elongation and torque. The analytical predictions match the simulation data well. Interestingly, we find a “thinning” regime where the torque has a very weak (logarithmic) dependence on the angular velocity. We discuss the origin of this behavior, which has no counterpart in polymers pulled by an applied force.
]Institute for Theoretical Physics, KU Leuven, Celestijnenlaan 200D, Leuven, Belgium \alsoaffiliationINFN, Sezione di Padova, Via Marzolo 8, Padova, Italy ]Department of Physics, Kyushu University, Fukuoka 819-0395, Japan \alsoaffiliationLaboratoire de Microbiologie et Génétique Moléculaires UMR 5100, CNRS & Université Paul Sabatier, F-31000 Toulouse, France
Understanding the dynamics of polymers at the nanoscale is a great challenge, which is not only interesting from the conceptual viewpoint, but also because it is useful for applications in nanotechnology. The challenge stems from the fact that even single polymers can display a complex dynamical behavior. A popular example is translocation through a nanopore, a process which has attracted quite some attention in the past years (see Panja et al. and Palyulin et al. 1, 2 for a review). In polymer translocation, the molecule is set into motion by an applied field at the pore side which acts as a linear pulling force.
While the dynamics of pulled polymers has been thoroughly studied, less attention has been devoted to the properties of polymers performing rotational motion, which can be induced by applying a torque. There are several examples in which the rotational motion of a polymer is of relevance. For instance, in the DNA double helix melting the two strands have to unwind from each other to separate. Another example is the transcription process, where RNA polymerase performs a rotational motion along the DNA axis wrapping the emergent mRNA molecule along the DNA 3, 4. The torque caused by relative rotation of the nascent RNA and DNA during transcription induces dynamic supercoiling in the transcribed DNA (“twin supercoiled domains”) which have a number of biological implications 5, 6. Also the closure of DNA bubbles involves rotational dynamics 7, 8 and rotational friction is involved in supercoil formation in DNA 9.
The aim of this paper is to investigate the torque-induced dynamics on a flexible polymer using a theoretical model based on torque-balance equations and computer simulations. We find a rich dynamical behavior where the polymer conformation is characterized by three different regimes, illustrated in 1. In general the theoretical predictions are in very good agreement with the simulation results and there are many analogies with the steady state motion of a polymer pulled by a force. In addition, the rotational motion is characterized by a “thinning” regime, which has no analogous counterpart in the dynamics of pulled polymers.
An isolated polymer in equilibrium is characterized by a single length scale, its Flory radius (where is the number of monomers and the monomer-monomer distance). In a polymer subject to confinement or to some external forces, instead, new length scales appear and the aforementioned global scaling generally breaks down. In these cases, the polymer can be described as being composed of blobs 10 of characteristic size . Depending on the system considered, the blobs can have constant size or their size may vary along the chain. According to the blob picture, the equilibrium scaling governed by the Flory exponent , still holds at distances below , while the effect of the external perturbation becomes apparent at higher distances. A classical illustration of the blob model is a polymer in equilibrium stretched by forces applied at the two end monomers and pointing in opposite direction 11. Here blobs have a characteristic homogeneous size , where is the applied force.
The blob model has been applied to many other equilibrium problems in polymer physics, for instance in modeling dense melts 10, polyelectrolytes stretched by an applied force 12, 13, polymers and biopolymers confined in nano-channels 14, 15, 16 and polymers adsorbed to surfaces 17. The blob model also provides a powerful tool to study polymer dynamics, a paradigmatic example being a polymer pulled by one end 18, 19, 20, 21, 22, 23 (briefly reviewed in the following section). Other out-of-equilibrium cases where the blob model has been applied include the already mentioned polymer translocation 24, 23, 22, the DNA hairpin folding 25, the DNA compression in a nanochannel 26 and the unwinding relaxation of a polymer from a fixed axis 27, 28, 29, 4.
This paper discusses the steady state dynamics of a flexible polymer performing a rotational motion around a fixed and impenetrable rod 4, 28. This motion is induced by a constant torque applied at the one end monomer that is attached to the rod. Hence it is different from the case in which the torque is applied to induce an internal twist dynamics on the polymer 9. We consider polymers containing simple single covalent bonds without twisting energy.
After an initial transient regime the polymer performs a steady rotation with a constant angular velocity , which is the rotational counterpart of the steady linear velocity of a polymer pulled by a constant force. To explain the steady state dynamics, we develop a blob model in which torsional blobs have a rotational origin. They have different scaling properties from the tensile blobs arising in stretched or dragged polymers. Our theory shows that, depending on the torque (or angular velocity), the polymer can assume different conformations. For low torques one finds an equilibrium regime (1(a)), followed by a trumpet regime at intermediate torques (1(b)) and a stem-trumpet regime at high (1(c)). Because of these regimes, the torque grows monotonically but not always linearly with the angular velocity. The theory is supported by Langevin dynamics computer simulations.
It is convenient to recall a few basic properties of polymers pulled at constant force, a case which has been well studied in the past 18, 19, 30, 31, 21, 23, 22. This will allow us to establish some useful scaling relations, which will be compared to those for polymers under torque. The comparison will be made through the introduction of torsional 4 blobs. Using the blob model we derive the relation between torque and rotational velocity. Finally the elongation of a self-avoiding polymer along the rod is investigated. Part of the theory of a stationary rotating polymer has already been developed in Ref. 4. Here we extend this theory to self-avoiding polymers and compute new quantities as the polymer elongation along the rod, which was not considered previously.
2.1 Tensile blobs
Consider a polymer, consisting of monomers, pulled by a constant force at one end. To label the monomers along the chain a coordinate is used: the polymer is pulled at , while is the free end. After a transient phase, the polymer arrives in the steady state, moving with a constant velocity . The force difference between two closely lying points and is then fully compensated by the friction. The force balance yields
where is the friction per monomer. Note that we focus here to the Rouse dynamics case, to which the simple relation (1) applies. With hydrodynamic interactions, the effect of the conformation dependent friction should be taken into account 22. The hydrodynamic case is briefly discussed at the end of this Section.
The differential equation (1) has solution , where we used the boundary condition . We obtain the following relation between the pulling force and the velocity:
The force is related to the blob size as
where we introduced a monomer-scale characteristic time
(throughout the paper we use the symbol to indicate a “quasi-equality” between two quantities, meaning that numerical prefactors of the order unity are neglected). Weak forces do not significantly perturb the shape of the polymer. The threshold force which produces a perturbation can be obtained from the requirement that the size of the initial blob, , exceeds the equilibrium radius of the polymer: . This leads to
For stronger forces the polymer consists of blobs of varying size and distributed from the free end according to (3), i.e. the blob size grows towards the free end. This so-called trumpet regime ends when the smallest blob has a size comparable to the monomer-monomer distance, i.e. . The trumpet regime appears for forces in the following range:
At higher forces,
part of the polymer close to the pulled monomer is stretched, while the end part still has the trumpet shape. For simplicity the boundaries between the three regimes were obtained using static criteria. We note that they can also be obtained from dynamic criteria involving the drift velocity of the polymer. For instance the equilibrium regime can be characterized from the requirement
where is the longest relaxation time. In the relation (8) we require that the distance covered by the polymer in a time equal to is smaller than its equilibrium radius, i.e. the polymer moves sufficiently slow so that it equilibrates while leaving a region of the size of its radius. It can be easily seen that (8) is identical to (5)). Analogous arguments can be used to derive (6) and (7)).
The three regimes characterized by the inequalities (5)-(7) are the tensile counterparts of those shown in 1 for polymers under torque. For comparison with the rotating polymer it is useful to compute the end-to-end extension of a polymer pulled by a force. In the trumpet regime (6), where the scaling (3) applies to the whole polymer, the end-to-end distance is given by
where is the number of monomers per blob. Note that at the threshold of the equilibrium regime the force-velocity relation (2) yields:
Substituting this expression in (9) we recover the equilibrium result .
2.2 Torsional Blobs
Consider now the rotational counterpart of a pulled polymer, where a torque is applied to the monomer attached to the rod 28. For weak torques we expect that, analogous to the case of a pulled polymer, the polymer will perform a rotational motion while maintaining its equilibrium shape. Using the threshold value for the polymer pulled by a constant force (5), an upper bound for the torque in the equilibrium regime is found:
Here is the characteristic value of the applied force and the equilibrium radius. Using , which relates linear to rotational velocity, together with the force-velocity expression (2), the inequality (11) can be rewritten:
This establishes the threshold value for the equilibrium regime for given and (the characteristic monomer-scale time, , is defined in (4)). Note the similarities of the previous inequality with (8): the inequality in (12) requires the relaxation of the rotating polymer while performing a fraction of a turn. It should be stressed that the condition for the equilibrium regime (11) is correct up to logarithmic terms which, because they are dimensionless, cannot be extracted from scaling considerations. A more accurate handling of these terms is reported in the Section discussing the dependence of the torque on .
We now use a torque balance argument to set up a differential equation for , the torque as a function of the monomer coordinate . This is the rotational version of (1), which related the force to in the tensile case. Consider a torsional blob of size which rotates around the rod at fixed angular velocity . The infinitesimal torque difference is , while the friction . The force balance then gives
Unlike in the pulling case, (1), the blob size appears in the previous equation, reflecting the fact that the rotational friction is conformation-dependent even without the hydrodynamic interactions. To close (13), we thus need to know the local relation between the torque and the torsional blob size. To this end we consider the equilibrium properties of a polymer wound around a rod.
The winding angle of a polymer attached to a rod is defined as times the number of turns the polymer performs around the rod, starting from the fixed end. In equilibrium the average winding angle vanishes by symmetry: . This variable is distributed according to the following scaling form 32, 33, 34, 35:
where is a scaling function. This form is generic, but the case of the two dimensional winding of an ideal polymer around a circle one has 33. For a two dimensional self-avoiding polymer 32, 34. In three dimensions the scaling for the ideal polymer remains . The equilibrium three dimensional self-avoiding polymer wound around the rod has been studied numerically 35 and data were fitted with . In the torque ensemble the probability distribution is obtained by a Laplace transform of (14):
with a scaling function. This relation implies that typical values scale as . Applying this result to the torsional blob with monomers, we get the torsional blob-torque relation
Differentiating the previous relation with respect of we find:
From (18) we get the threshold for the different regimes in the same way as for tensile blobs. Again, the equilibrium regime ends when the equilibrium polymer radius is equal to the size of the initial blob , i.e. . From this relation, and using (18), we get again (12). The boundary between the trumpet and stem-trumpet regime is obtained when , which yields
In summary: we expect three distinct regimes, with boundaries given by the analysis above. These regimes are also depicted in 1.
If , the polymer rotates while maintaining its equilibrium shape.
If the polymer assumes a trumpet shape in its full length. It is composed of torsional blobs of decreasing size starting from the free polymer end .
If the polymer assumes a trumpet shape in a limited range , while the monomers close to the tethered point, , are fully wrapped around the rod. This marks the stem-trumpet regime. , the boundary between stem and trumpet, can be obtained from the relation , thus:
Note that the size of the blob diverges as . To avoid divergences in the following calculations we compute , the size of the ‘last’ blob, containing monomers. The size can be obtained using the blob scaling (18) (recall that is the free end) and the equilibrium properties of the last blob ():
Rewriting yields expressions for and :
At the threshold between equilibrium and trumpet regime and from (22) one then finds , i.e. the last blob ‘covers’ the whole polymer.
2.3 Torque vs. angular velocity
The analysis of the previous section can be used to compute the total torque applied as a function of the angular velocity. The fact that the rotational friction depends on the conformation leads to a non-trivial dependence of on .
To calculate the torque in the trumpet regime we integrate Eq. (17). We use as integration variable, hence the interval corresponds to , as the last blob size formally diverges in the limit . Here denotes the size of the first blob. As (17) was obtained from the differentiating (16) we get:
Using (18) we obtain:
which is a very weakly increasing function of .
We have used Eq. (11) to estimate the boundary between the equilibrium and trumpet regimes. Alternatively we can estimate this boundary by equating the torques of (25) and (26) and assuming that the polymer consists of a single blob . We obtain
hence the rotating polymer is in equilibrium for torques
Compared to (12) the previous relation contains a logarithmic term. In practice this term does not affect strongly the estimate of the boundary of the equilibrium regime. However the estimate (28) is more accurate as it can be seen from a following argument. We can estimate the boundary using
where is the stationary winding angle of the rotating polymer. Eq. (30) is the rotational counterpart of the relation (see (5)) which is an estimate of the boundary of the equilibrium regime for a polymer pulled by a force on one end ( is the Flory radius). In the rotating case the polymer does not display a substantial deformation compared to equilibrium when the average winding is smaller than that from equilibrium fluctuations in absence of torque. The boundary of the equilibrium regime can be estimated by equating the average winding angle induced by the torque to the equilibrium value in absence of torque as follows:
Now, is obtained from (30), using the torque for the equilibrium regime (25). As equilibrium fluctuations are described by the scaling form (14) we get . Combining these results we get again the relation (28).
In the stem-trumpet regime the polymer is assumed to form a tight helix for , where is given by (20) and a trumpet for . The contribution of the torque from the stem can be obtained by integrating (18) where the blob size fixed to , with the radius of the rod. One finds . The trumpet part contributes to the torque as (27), with replacing . Combining these two contributions results in:
In this regime the torque is again, to leading order, proportional to . Eq. (19) provides an estimate of the boundary between the trumpet and the stem-trumpet regimes. If this relation is used as a strict equality one gets a divergence of (27). Analogously, (32) is divergent when (20) is used as a strict equality. In order to avoid such effects we used in both cases a different cutoff and , where . The torque in the trumpet regime is therefore bounded in the interval:
In summary: the torque-angular velocity relation is highly non-trivial, as depicted in 2. At weak and high torques, respectively the equilibrium and stem-trumpet regimes, is proportional to . This can be directly seen in (25) and (32) (in the latter case this proportionality holds in leading order for large ). Both regimes are characterized by two different rotational friction coefficients and , with different dependencies on the polymer length: and . In the intermediate trumpet regime there is a strong “thinning” behavior with increasing very weakly with . Here the polymer decreases its resistance to the rotational motion by getting closer to the rod axis. This contrasts the stretching by a linear force, where the force-velocity relation is always linear for Rouse dynamics, as can be seen by inspection of the force-velocity relation (2). Only for chains with hydrodynamic interactions, a non-linear force-velocity relation is obtained 22.
2.4 Polymer elongation
A self-avoiding polymer is expected to, at sufficiently high torque, elongate as a helix along the rod. The blob theory developed in the previous section can be used to compute the elongation in the three regimes. The elongation, denoted by , is defined as the distance between the two end monomers along the rod direction. In the calculations we can safely use the leading order form for the blob size (18), ignoring higher order logarithmic terms.
In the equilibrium regime the polymer maintains its equilibrium shape, hence
In the trumpet regime one can simply sum up the contribution of the different blobs:
where is the number of monomers in the blob. In the calculation there is no need to separate the contribution of the last blob as the singularity in is integrable. Using and (18), we can evaluate the integral:
This is the rotational counterpart of (9), which was derived for pulled polymers. The boundary between the equilibrium and the trumpet regime is characterized by the relation . Substituting this boundary condition in (36) gives , as expected in the equilibrium regime. Hence (36) merges with (34) at the phase boundary.
In the stem-trumpet regime the first monomers, counting from the end attached to the rod, are fully wrapped around the rod, while the last are in a trumpet conformation. Assuming that in the stem the elongation per monomer is , we find
where we have used (20): . To show the compatibility of (36) and (37), we plug in , which marks the phase boundary between trumpet and stem-trumpet regime. It is clear that both expressions then coincide at .
In summary: when the polymer is performing an equilibrium rotation, the elongation along the rod axis is dictated by the random coil value. Upon entering the trumpet regime, blobs start to form and grows as . Finally, in the stem-trumpet regime the polymer is wrapped around the rod and asymptotically . Note that in an ideal chain monomers can pass through each other, thus there is no helix formation and the previous calculations are not at issue.
The results presented above can be extended to the hydrodynamic case. A blob of size moving with velocity now experiences a friction propotional to its size, , while without hydrodynamics the friction scales with the number of monomers in a blob. The contribution of a small segment of the polymer to the friction force is then
Hence the torque balance () reads
which is the counterpart of (13).
(17) was derived from local equilibrium input, hence it remains valid in the hydrodynamic case. Combining (17) and (39) results in a differential equation for . The solution, neglecting again logarithmic terms, is
Using the Flory exponent we get . This is a more rapid decay of the blob size than in the Rouse case , see Eq.(18).
Using (40) we can calculate the scaling behavior of various quantities in the hydrodynamic case. Note that (26) implies that still depends logarithmically on in the trumpet regime. Another interesting quantity to compute is the elongation in the trumpet regime:
3 Numerical Simulations
Numerical simulations were performed using the LAMMPS package 36. Due to the large computational cost of simulating systems with hydrodynamics interactions, we restrict our analysis to simulations of Rouse polymers. The polymer was modeled using a bead spring model with a finitely extensible nonlinear elastic (FENE) interaction 37 between successive beads, so that a maximal distance between bonds is imposed. The rod was modeled by defining a cylindrical region with radius around the z-axis and adding soft repulsive interaction of Weeks-Chandler-Andersen (WCA) type 38. Because the maximal distance between beads is chosen smaller than the diameter of the rod, it is impossible for bonds to cross through the rod.
In order to impose a constant torque we introduced a ‘ghost’ particle at the origin of the axes, i.e. within the rod. A second particle was kept at a constant distance from it using the SHAKE algorithm 39. The distance was set equal to , the radius of the rod. A constant force was applied to the second particle, which corresponds to the first bead of the polymer. This force was oriented perpendicular to the plane defined by the rod and the axis connecting this first bead and the ghost particle. The applied torque equals then . Furthermore LJ units of LAMMPS were used, such that . In these units the two parameters controlling the repulsive Lennard-Jones part of the FENE potential (usually called and ) are also set to one. Then we chose to set . The maximal bond length, controlled by the FENE potential, was set to 1.5.
The system was integrated using the fix nve and fix langevin commands in LAMMPS, which corresponds to performing a Langevin dynamics simulation. Time integration is realized using a velocity Verlet updating scheme. The coupling to the heat bath is implemented through the thermostat described in Schneider and Stoll40 and Dunweg and Paul41. Simulations were performed for different torques and for lengths up to . 3 shows two snapshots of the simulations, representing the two models used in the simulations: ideal polymers (left) and self-avoiding polymers (right). In the latter case an additional WCA potential was added.
In the simulations the torque is fixed and applied to the anchored monomer. Thus there are no numerical errors on . The angular velocity was instead determined from the simulation runs. For every value of the applied torque the simulation was run for a significantly long time, such that the stationary state was reached. The angular velocity was determined by counting the number of turns a monomer made in a given time interval, multiplying this number by and dividing by the length of the time interval. Monomers close to the attached end have larger fluctuations, so was estimated by averaging over the end monomers.
In this section we focus on three observables. The first is the blob size along the rod. Due to its interesting properties, a separate section for the size of the last blob is added. Then the focus shifts to the torque versus angular velocity relation. Finally the elongation of a SAW along the rod is presented.
3.1 Blob size vs.
First of all we are interested in the blob size. A good estimator for this blob size is the average distance of each monomer from the rod. As the rod is oriented along the z-axis we have
where and represent the x- and y-coordinate of the -th monomer.
In 4(a), vs. is presented for four different values of the applied torque, for ideal polymers. These four cases are labeled from 1 to 4, ordered according to increasing applied torque. We estimated the stationary angular velocity , for the different cases, as presented in the caption, from the ratio of the number of turns of each monomer over the simulation time.
For case 1, the weakest applied torque, the polymer has an equilibrium shape characterized by random coil scaling (recall that is the free end):
with for ideal polymers. In this case we estimate , using and setting as given in the caption of 4. Since , this should correspond to the trumpet regime - according to the analysis in the theory section. However, the theory is based on scaling arguments and the relations are valid up to some numerical prefactors. This first case (1) suggests that the trumpet regime sets in at ’s a bit higher than predicted by (12).
When higher torques are applied (cases 2-4) the stationary shape gets distorted from the equilibrium. The polymer gets wrapped around the rod, but close to the free end the shape is well fitted by (43), indicating that the free end is equilibrated. For case 4 we get , indicating that the system is close to the onset of the stem-trumpet regime, see (19).
which supports the scaling form of (18). In fitting the data we used a non vanishing intercept , due to the correction from the last blob. In case 2 the last blob seems to be extended to the whole polymer and the scaling cannot be clearly observed. We have fitted the data of vs. in the range of values where this relation is linear using a two-parameter fit on (44). The slope coefficient as a function of is shown in the inset of 4(b). This quantity increases linearly with in agreement with the prediction of (18). A similar analysis was performed for self-avoiding polymers. The results are in agreement with the blob theory and are shown in 5(a,b). Close to the free end the polymer exhibits equilibrium scaling (5(a)). The plot vs. (5(b)) shows the characteristic scaling behavior of torsional blobs (18).
3.2 The last blob
We focus now on the size of the last blob . In the trumpet regime, according to (22), , while in the equilibrium case . We can connect the two regimes using the following ansatz:
where is a scaling function and the scaling variable , which is the natural combination of and (see (12)). The equilibrium regime is recovered in the limit of small if . For large we require:
to recover (22). Note that the last blob is insensitive to the transition from the trumpet to the stem-trumpet regime.
We determine the size of the last blob from simulation data using (42) for . 6 shows a plot of vs. for (a) ideal polymers () and (b) self-avoiding polymers (). The data for various polymer lengths collapse into a single curve in agreement with the scaling behavior predicted by the scaling ansatz (45). For large values of the data follow the prediction of (46). The arrows in 6 show the estimated transition point from the equilibrium to the trumpet regime (, where we set ). Again the onset of the trumpet regime occurs at somewhat higher values of and than those predicted from the analytical arguments.
7 shows a plot of the applied torque vs. (a) and vs. (b) as obtained for the simulations for polymers of various lengths (we consider here only the case of ideal polymers ()). The lines are the plots of the blob theory predictions ((25), (27) and (32)) for a polymer of length . At low and high torques, the torque is proportional to the angular velocity, which is in agreement with the predictions of (25) and (32). The two regimes are separated by an intermediate (trumpet) regime, where “thinning” occurs: the torque increases more slowly than linear in . In the low torque (equilibrium) regime the data from polymers of various lengths collapse when plotted as function of (7(b)), in agreement with (25). At higher torques the data collapse when plotted as functions of (7(a)), which is again in agreement with (27) and (32). There is an overall quite satisfactory quantitative agreement between theory and simulations, keeping into account that we use no adjustable parameters in (25), (27) and (32) (we used as estimated from our simulations units). Comparing the simulations with the torsional blob theory predictions, we find that the differences are at most within a factor three. We recall that the torque-balance arguments in the blob theory are based on quasi-equalities which ignore unknown numerical prefactors which are expected to be of the order of unity. A more detailed test of the dependence of on in the trumpet regime (as predicted by (27)) is at the moment not possible because logarithmic dependences are notoriously difficult to establish as they require very long polymers.
3.4 Elongation along the rod
The elongation of the polymer along the rod was computed only for the case of self avoidance where 10 . In the simulation we determined the average absolute distance between the -coordinates of the first and last monomer, so the elongation is defined as
As we are interested in the behavior of in the trumpet and stem-trumpet regimes we plot in 8 vs. for polymers of various lengths. For self-avoiding polymers the theoretical prediction (36) implies . In the stem trumpet regime, (37) yields to leading order in : . The crossover between these two regimes around (19) is indeed observed in 8, where the data belonging to polymers of different lengths collapse into a single curve.
In this paper, we gave a full description of the stationary rotation of a flexible polymer induced by a torque. Using a local torque-balance equation, we computed the polymer shape as a function of the curvilinear coordinate . We identify three regimes as the angular velocity increases (or equivalently, when the torque applied to the monomer attached to the rod increases). (i) The equilibrium regime, where the polymer is not perturbed from its equilibrium configuration. (ii) The trumpet regime, in which the polymer is composed of blobs of decreasing size, starting from the free end. Here the blob size decays as , which is much slower than the case of a constant force applied at one end (). Finally (iii) the stem-trumpet regime is defined when a part of the polymer close to the attached monomer is tightly wound around the axis while the free end still displays a trumpet shape.
One of the central results of this paper is the characterization of the response of the total torque to a change of the angular velocity or the number of monomers . In the equilibrium and the stem-trumpet regime, the torque is proportional to the angular velocity . The torque friction, , has a different scaling behavior with the polymer length in equilibrium compared to the stem-trumpet regime . More surprisingly, in the trumpet regime the torque has a very weak (logarithmic) dependence on . This dependence stems from the fact that when the torque is increased the polymer gets closer to the central axis hereby reducing the resistance to the rotational motion. Non-power law, and specifically logarithmic, behavior has already been predicted, simulated and observed in the case of polymer stretching.12, 13 However, in that case a situation where both ends are subjected to a force is studied and the logarithmic dependence represents an increase of resistance for high forces due to short-scale DNA crumpling. The setup we consider is different: the resistance decreases in an intermediate torque regime, due to the decrease in distance between the polymer and the rod.
The torque-torsional blob relation (16) is an analogue of the well-known force-tensile blob relation in the pulling problem 11, and is expected to play an essential role to further explore the rotational dynamics. It would be interesting to check experimentally the predictions of the theory. The experimental protocol could be achieved with excitable cylinders in an optical torque wrench 42. A polymer could be attached to the cylinder and the other end of the polymer labelled with a fluorescent molecule, allowing, e.g., to test the dependence of spacing of the free end from the axis of rotation with respect to the angular velocity.
B.B. acknowledges the support of Grant No CA077712 from the National Cancer Institute, NIH to the Hanawalt laboratory at Stanford University. T.S. is supported by KAKENHI [Grant No.26103525, “Fluctuation and Structure”, Grant No.24340100, Grant-in-Aid for Scientific Research (B)], Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan and JSPS Core-to-Core Program (Nonequilibrium Dynamics of Soft Matter and Information). J-C.W. acknowledges the support by the Laboratory of Excellence Initiative (Labex) NUMEV, OD by the Scientific Council of the University of Montpellier.
Table of Contents graphic
Torque-induced rotational dynamics in polymers: Torsional blobs and thinning
Michiel Laleman, Marco Baiesi, Boris P. Belotserkovskii, Takahiro Sakaue, Jean-Charles Walter and Enrico Carlon
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